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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM5 All Species: 22.73
Human Site: S250 Identified Species: 55.56
UniProt: P41594 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41594 NP_000833.1 1212 132469 S250 A H S Y K I Y S N A G E Q S F
Chimpanzee Pan troglodytes XP_001135787 1210 132280 S250 A H S Y K I Y S N A G E Q S F
Rhesus Macaque Macaca mulatta A3QP01 839 95041
Dog Lupus familis XP_848683 1238 133938 S250 A H S Y K I Y S N A G E Q S F
Cat Felis silvestris
Mouse Mus musculus Q3UVX5 1203 131847 S249 A H S Y K I Y S N A G E Q S F
Rat Rattus norvegicus P31424 1203 131867 S249 A H S Y K I Y S N A G E Q S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511915 1153 127609 A242 E A F K D M S A K E G I C I A
Chicken Gallus gallus NP_989469 1242 138045 S256 A H S Y K I Y S N A G E Q S F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 L78 V Q R L E A M L Y A I D R V N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 21.3 95.1 N.A. 95.5 95.3 N.A. 88.7 84.2 N.A. 20.3 N.A. 32.7 N.A. N.A. N.A.
Protein Similarity: 100 99.7 36.7 95.8 N.A. 96.3 96.1 N.A. 91.3 88.8 N.A. 36.2 N.A. 48.5 N.A. N.A. N.A.
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 6.6 100 N.A. 0 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. 20 100 N.A. 0 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 60 10 0 0 0 10 0 10 0 70 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 10 0 0 0 10 0 0 0 0 10 0 60 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 60 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 70 0 0 0 0 % G
% His: 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 60 0 0 0 0 10 10 0 10 0 % I
% Lys: 0 0 0 10 60 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 60 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 0 0 60 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 0 0 60 0 0 0 10 60 0 0 0 0 0 60 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 60 0 0 60 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _